TGF-β1 ELISA kit | Enzo Life Sciences ADI-900-155 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

TGF-β1 ELISA kit

catalog :

ADI-900-155

quantity :

96 wells

citations: 3

Reference
Moraes L, FranÃ§a E, Pessôa R, Fagundes D, Hernandes M, Ribeiro V, et al. The effect of IFN-Î³ and TGF-Î² in the functional activity of mononuclear cells in the presence of Entamoeba histolytica. Parasit Vectors. 2015;8:413 pubmed publisher
Choi S, Nam J, Jang J, Lee H, Lee Y. Pirfenidone enhances the efficacy of combined radiation and sunitinib therapy. Biochem Biophys Res Commun. 2015;462:138-43 pubmed publisher
Morales M, Vazquez Y, Acuña M, Rivera J, Simon F, Salas J, et al. Angiotensin II-induced pro-fibrotic effects require p38MAPK activity and transforming growth factor beta 1 expression in skeletal muscle cells. Int J Biochem Cell Biol. 2012;44:1993-2002 pubmed publisher

product information

Product ID :

ADI-900-155

Catalog Number :

ADI-900-155

Product Name :

TGF-β1 ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

26249205, 25935484, 22964022

Product Description :

The TGF-β1 EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 4 hours. Absorbance is read at 450 nm. This kit provides ultra-sensitive measurement of as little as 3.3 pg/mL TGF-β1 and has been fully validated in activated serum, plasma, and culture supernatants. The ready-to-use liquid color-coded reagents reduce error.

SPECIES REACTIVITY :

Human, Mouse, Rat, Bovine

Background :

Transforming growth factor beta 1 is also known as TGFβ1, TGF β, and TGFB. The inactive form consists of a TGF-β1 homodimer that is non-covalently linked to a latency-associated peptide homodimer. The active form is a homodimer of mature TGF-β1 that is disulfide linked. The precursor is cleaved into mature TGF-β1 and the latency-associated peptide. Many cells can synthesize TGF-β1, which is secreted to function in proliferation, differentiation, transformation, signaling and apoptosis. This cytokine has been implicated in many diseases including diabetes, renal disease, chronic pulmonary obstructive disease, as well as many cancers including prostate, and colon. This protein is a potential tumor-specific cancer therapeutic. Specifically, as a stable soluble dimer, it selectively induces apoptosis in many transformed cells, but not in normal cells. The literature contains many reviews on the biology and function of TGF-β1.

ALTnames :

Transforming growth factor β 1

Uses :

For the quantitative determination of TGF-β1 in culture supernatants, plasma, and serum of human, mouse, rat, and cow origin.

Application Summary :

ELISA, Colorimetric detection