Erk1/2 ELISA kit | Enzo Life Sciences ADI-900-152 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

Erk1/2 ELISA kit

catalog :

ADI-900-152

quantity :

96 wells

product information

Product ID :

ADI-900-152

Catalog Number :

ADI-900-152

Product Name :

Erk1/2 ELISA kit

Product Type :

Kit

Size :

96 wells

Product Description :

The Erk1/2 EIA Kit is a complete assay for the quantitative determination of pan Erk1/2 concentration.

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

ERK1 and ERK2 constitute a subset of the mitogen-activated protein kinase (MAPK) pathway. Also called p44 and p42, respectively, these molecules function to connect cell surface receptors to nuclear transcription factors, which in turn regulate and control a number of fundamental cellular processes. ERK1 and ERK2 may be stimulated by cytokines, growth factors, irradiation, osmolarity or temperature fluctuations, or physical stress. The upstream MAP kinases MEK1 and MEK2 activate ERK1 and ERK2 via dual phosphorylation at the conserved T-E-Y motif found at the human Thr202/Tyr204 sequence or the rat and mouse Thr183/Tyr185 sequence. Activated MAP kinases translocate to the nucleus, where they may phosphorylate a wide range of transcription factors that regulate processes including proliferation, apoptosis, survival, and differentiation. The literature contains numerous and extensive reviews on MAP kinases.

ALTnames :

MAPK2/3, MAP kinase 2/3

Uses :

For the measurement of Erk1/2 in cell lysates of human, mouse, and rat origin.

Application Summary :

ELISA, Colorimetric detection