β-Catenin ELISA kit | Enzo Life Sciences ADI-900-135 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

β-Catenin ELISA kit

catalog :

ADI-900-135

quantity :

96 wells

citations: 3

Reference
Ali M, El Abhar H, Kamel M, Attia A. Antidiabetic Effect of Galantamine: Novel Effect for a Known Centrally Acting Drug. PLoS ONE. 2015;10:e0134648 pubmed publisher
Allameh A, Dadkhah A, Rahbarizadeh F, Ashrafi Helan J, Fatemi F. Effect of dietary caraway essential oils on expression of ?-catenin during 1,2-dimethylhydrazine-induced colonic carcinogenesis. J Nat Med. 2013;67:690-7 pubmed publisher
Santos A, Bakker A, Zandieh Doulabi B, de Blieck Hogervorst J, Klein Nulend J. Early activation of the beta-catenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase. Biochem Biophys Res Commun. 2010;391:364-9 pubmed publisher

product information

Product ID :

ADI-900-135

Catalog Number :

ADI-900-135

Product Name :

β-Catenin ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

26262991, 22418855, 19913504

Product Description :

The β-Catenin EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours that measures pan β-Catenin. Absorbance is read at 450 nm. This kit has been validated in-house with human, mouse, and rat cell lysates and correlated Western blot. The β-Catenin EIA kit detects as little 27 pg/mL β-catenin surpassing semi-quantitative Western blot analysis and provides simple liquid color-coded reagents that reduce laboratory error.

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

β-catenin is a 781 amino acid adherens junction protein that plays an important role in two unrelated cellular functions. Adherens junctions are critical for establishment and maintenance of epithelial layers, such as those found lining the surface of organs. Involved in both cell-cell adhesion and in the wnt/wg signaling pathway, β-catenin can be found in the cytoplasm or the nucleus. In the cytoplasm, β-catenin is unstabilized by phosphorylation and association with E-cadherin. When β-catenin translocates to the nucleus, it has comparatively low levels of phosphorylation. Wnt/wg signaling results in β-catenin accumulation and transcriptional activation of specific target genes during development. Deregulation of β-catenin signaling is an important event in the evolution a number of malignancies, including colon cancer, melanoma, ovarian cancer, and prostate cancer. The homology between human, mouse and rat β-catenin is 99.9%.

ALTnames :

Cadherin-associated protein

Uses :

For the quantitative determination of β-Catenin in cell lysates of human, mouse, and rat origin.

Application Summary :

ELISA, Colorimetric detection