MEK1 ELISA kit | Enzo Life Sciences ADI-900-122A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

MEK1 ELISA kit

catalog :

ADI-900-122A

quantity :

96 wells

product information

Product ID :

ADI-900-122A

Catalog Number :

ADI-900-122A

Product Name :

MEK1 ELISA kit

Product Type :

Kit

Size :

96 wells

Product Description :

The MEK1 EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours that measures pan MEK1. Absorbance is read at 450 nm.

SPECIES REACTIVITY :

Human, Rat

Background :

MEK1 is also known by a variety of other names. They include dual specificity mitogen-activated protein kinase kinase (MAP kinase kinase 1 or MAPKK 1), ERK activator kinase 1, MAPK/ERK kinase 1, ERK kinase 1 and MAP kinase kinase. MEK1 is a 393 amino acid, 43.5kD protein that is highly conserved in evolution. MEK phosphorylates threonine and tyrosine residues on MAP kinases ERK 1 and 2 (p44 and p42 MAP kinase). MEK participates in a wide range of cellular processes including cell proliferation, differentiation and apoptosis. MEK1 is activated by phosphorylation of Ser218 and Ser222 by the serine-threonine kinase RAF1, which is part of the p21ras signal transduction pathway. Constitutive activation of MEK1 results in cellular transformation. This protein kinase has been reported to be a likely target for pharmacological intervention in proliferative diseases.

ALTnames :

MAPK2K1, MAPKK1, MAP kinase kinase 1, MAPK/ERK kinase 1

Uses :

For the quantitative determination of MEK1 in cell lysates of human and rat origin.

Application Summary :

ELISA, Colorimetric detection