Osteopontin (rodent), ELISA kit | Enzo Life Sciences ADI-900-090A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

Osteopontin (rodent), ELISA kit

catalog :

ADI-900-090A

quantity :

96 wells

citations: 4

Reference
Carlos C, Sonehara N, Oliani S, Burdmann E. Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model. PLoS ONE. 2014;9:e103660 pubmed publisher
Lyle A, Remus E, Fan A, LASSEGUE B, Walter G, Kiyosue A, et al. Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. J Biol Chem. 2014;289:275-85 pubmed publisher
Topkoru B, Altay O, Duris K, Krafft P, Yan J, Zhang J. Nasal administration of recombinant osteopontin attenuates early brain injury after subarachnoid hemorrhage. Stroke. 2013;44:3189-94 pubmed publisher
Narisawa S, Yadav M, Millan J. In vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontin. J Bone Miner Res. 2013;28:1587-98 pubmed publisher

product information

Product ID :

ADI-900-090A

Catalog Number :

ADI-900-090A

Product Name :

Osteopontin (rodent), ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

24247243, 24008574, 23427088

Product Description :

The Osteopontin (rodent), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours.

SPECIES REACTIVITY :

Mouse, Rat

Background :

Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to be a positive indicator of colon and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

ALTnames :

OPN, SPP1, Secreted phosphoprotein 1, Bone sialoprotein 1

Uses :

For the quantitative determination of mouse and rat osteopontin in culture supernatants, plasma, and urine. Cited sample type includes cerebrospinal fluid.

Application Summary :

ELISA, Colorimetric detection

Storage :

+4°C