This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
ELISA/assay
product name :
Big Endothelin-1 (rat), ELISA kit
catalog :
ADI-900-073
quantity :
96 wells
citations: 2
Reference
Ko A, Hyun H, Min S, Kim J, Kang T. Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity. Mol Brain. 2015;8:58 pubmed publisher
Alici O, Kavakli H, Koca C, Altintas N, Aydin M, Alici S. Value of caffeic acid phenethyl ester pretreatment in experimental sepsis model in rats. Mediators Inflamm. 2015;2015:810948 pubmed publisher
product information
Product ID :
ADI-900-073
Catalog Number :
ADI-900-073
Product Name :
Big Endothelin-1 (rat), ELISA kit
Product Type :
Kit
Size :
96 wells
list of Pubmed id :
26438559, 25948886
Product Description :
The Big Endothelin-1 (rat), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results overnight + 1 hour.
SPECIES REACTIVITY :
Rat
Background :
Endothelins (ET) are isopeptides produced by vascular endothelium that have potent vasoconstrictive activity. The peptides are encoded by three separate genes and processed to yield 39-residue "Big ET" molecules which are further processed to the 21 amino acid sequences designated ET-1, ET-2 and ET-3. ET action is mediated via binding to two receptors, ETA and ETB. Activation of ETA increases vasoconstriction and sodium retention, thereby increasing blood pressure. Activation of ETB receptors triggers the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells and increases urine production and elimination, thereby lowering blood pressure.
ALTnames :
Big ET-1
Uses :
For the quantitative determination of rat Big ET-1 in culture supernatants, plasma, and serum.
Application Summary :
ELISA, Colorimetric detection
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.