Complement C3a des Arg (human), ELISA kit | Enzo Life Sciences ADI-900-058 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

Complement C3a des Arg (human), ELISA kit

catalog :

ADI-900-058

quantity :

96 wells

product information

Product ID :

ADI-900-058

Catalog Number :

ADI-900-058

Product Name :

Complement C3a des Arg (human), ELISA kit

Product Type :

Kit

Size :

96 wells

Product Description :

The Complement C3a des Arg (human), EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours. Absorbance is read at 405 nm. This kit comes ready-to-use with sample preparation reagents included. The Complement C3a des Arg (human), EIA kit is specific, offering low cross-reactivity to structurally related molecules, and sensitive with quantification of as little as 120 pg/mL Complement C3a des Arg.

SPECIES REACTIVITY :

Human

Background :

Activation of the complement cascade is initiated by multiple pathways, including C1q binding of antigen-antibody complexes on pathogens (classical pathway), binding of serum lectin to pathogen-unique mannose residue patterns (MBL pathway), or the spontaneous hydrolysis of C3 and subsequent processing to C3 convertase (alternative pathway). C3a and C4a are two complement cleavage products of 77- and 76-amino acid residues, respectively, that are liberated into the bloodstream and processed to their more stable metabolites C3a des Arg and C4a des Arg. Although both fragments have anaphylactic properties, C3a is considered a more potent stimulator of smooth muscle cell contraction, histamine release, and inflammation than C4a. Complement activation is associated with sepsis, respiratory distress syndrome, multi-organ failure, and transplant organ rejection.

Uses :

For the quantitative determination of Complement C3a des arg in human EDTA plasma.

Application Summary :

ELISA, Colorimetric detection