Endothelin-1 ELISA kit | Enzo Life Sciences ADI-900-020A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

Endothelin-1 ELISA kit

catalog :

ADI-900-020A

quantity :

96 wells

citations: 15

Reference
Lee G, Hosgood S, Patel M, Nicholson M. Hydrogen sulphide as a novel therapy to ameliorate cyclosporine nephrotoxicity. J Surg Res. 2015;197:419-26 pubmed publisher
Jain A, Schneider H, Aliyev E, Soydemir F, Baumann M, Surbek D, et al. Hypoxic treatment of human dual placental perfusion induces a preeclampsia-like inflammatory response. Lab Invest. 2014;94:873-80 pubmed publisher
Star G, Giovinazzo M, Lamoureux E, Langleben D. Effects of vascular endothelial growth factor on endothelin-1 production by human lung microvascular endothelial cells in vitro. Life Sci. 2014;118:191-4 pubmed publisher
Pan X, Grigoryeva L, Seyrantepe V, Peng J, Kollmann K, Tremblay J, et al. Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1. PLoS Genet. 2014;10:e1004146 pubmed publisher
Faraco G, Wijasa T, Park L, Moore J, Anrather J, Iadecola C. Water deprivation induces neurovascular and cognitive dysfunction through vasopressin-induced oxidative stress. J Cereb Blood Flow Metab. 2014;34:852-60 pubmed publisher
Feng B, Cao Y, Chen S, Ruiz M, Chakrabarti S. miRNA-1 regulates endothelin-1 in diabetes. Life Sci. 2014;98:18-23 pubmed publisher
Barden A, Croft K, Beilin L, Phillips M, Ledowski T, Puddey I. Acute effects of red wine on cytochrome P450 eicosanoids and blood pressure in men. J Hypertens. 2013;31:2195-202; discussion 2202 pubmed publisher
Kotani T, Iwase A, Tsuda H, Mano Y, Yamamoto E, Nakano T, et al. Altered expression of enzymes regulating the activity of endothelin-1 in the lower segment of the human amnion during labor. Biol Reprod. 2013;89:52 pubmed publisher
Yoshikawa N, Shimizu N, Maruyama T, Sano M, Matsuhashi T, Fukuda K, et al. Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice. PLoS ONE. 2012;7:e52522 pubmed publisher
Thompson L, Frasier C, Sloan R, Mann E, Harrison B, Brown J, et al. Pulmonary instillation of multi-walled carbon nanotubes promotes coronary vasoconstriction and exacerbates injury in isolated hearts. Nanotoxicology. 2014;8:38-49 pubmed publisher
Choritz L, Machert M, Thieme H. Correlation of endothelin-1 concentration in aqueous humor with intraocular pressure in primary open angle and pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci. 2012;53:7336-42 pubmed publisher
Yeager M, Reddy M, Nguyen C, Colvin K, Ivy D, Stenmark K. Activation of the unfolded protein response is associated with pulmonary hypertension. Pulm Circ. 2012;2:229-40 pubmed publisher
Alvarez D, Briassouli P, Clancy R, Zavadil J, Reed J, Abellar R, et al. A novel role of endothelin-1 in linking Toll-like receptor 7-mediated inflammation to fibrosis in congenital heart block. J Biol Chem. 2011;286:30444-54 pubmed publisher
Sweazea K, Walker B. High fat feeding impairs endothelin-1 mediated vasoconstriction through increased iNOS-derived nitric oxide. Horm Metab Res. 2011;43:470-6 pubmed publisher
Farina G, York M, Collins C, Lafyatis R. dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts. Ann Rheum Dis. 2011;70:544-50 pubmed publisher

product information

Product ID :

ADI-900-020A

Catalog Number :

ADI-900-020A

Product Name :

Endothelin-1 ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

25990693, 24933425, 24607779, 24517977, 24394957, 24096258, 23863409, 23300697, 23036995, 21730058

Product Description :

The Endothelin-1 EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours. This ultra-sensitive kit lets you quantify as little as 0.41 pg/mL ET-1 in a variety of biological matrices with the option of overnight or a 1 hour primary incubation.

SPECIES REACTIVITY :

Human, Mouse, Rat, Rabbit, Porcine, Dog, Bovine

Background :

Endothelins (ET) are isopeptides produced by vascular endothelium that have potent vasoconstrictive activity. The peptides are encoded by three separate genes and processed to yield 39-residue "Big ET" molecules which are further processed to the 21 amino acid sequences designated ET-1, ET-2 and ET-3. ET action is mediated via binding to two receptors, ETA and ETB. Activation of ETA increases vasoconstriction and sodium retention, thereby increasing blood pressure. Activation of ETB receptors triggers the release of vasorelaxive factors such as nitric oxide (NO) and prostanoids from endothelial cells and increases urine production and elimination, thereby lowering blood pressure.

Uses :

For the quantitative determination of ET-1 in culture supernatants, plasma, and serum of human, mouse, rat, cow, dog, pig, and rabbit origin. Cited sample types include cell lysates and tissue homogenates.

Application Summary :

ELISA, Colorimetric detection

Storage :

+4°C