product summary
company name :
Echelon Biosciences
product type :
antibody
product name :
Purified Anti-PtdIns (4,5)P2 IgM
catalog :
Z-P045
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunocytochemistry
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; fig s3
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig s5b
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
  • immunocytochemistry; mouse
Ko H, Guo L, Su B, Gao L, Gelman I. Suppression of chemotaxis by SSeCKS via scaffolding of phosphoinositol phosphates and the recruitment of the Cdc42 GEF, Frabin, to the leading edge. PLoS ONE. 2014;9:e111534 pubmed publisher
Du X, Zhou L, Aw Y, Mak H, Xu Y, Rae J, et al. ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets. J Cell Biol. 2020;219: pubmed publisher
Wan Z, Xu C, Chen X, Xie H, Li Z, Wang J, et al. PI(4,5)P2 determines the threshold of mechanical force-induced B cell activation. J Cell Biol. 2018;217:2565-2582 pubmed publisher
Chen D, Yang C, Liu S, Hang W, Wang X, Chen J, et al. SAC-1 ensures epithelial endocytic recycling by restricting ARF-6 activity. J Cell Biol. 2018;217:2121-2139 pubmed publisher
Ghai R, Du X, Wang H, Dong J, Ferguson C, Brown A, et al. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nat Commun. 2017;8:757 pubmed publisher
Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed publisher
company information
Echelon Biosciences
675 Arapeen Dr. Ste. 302 Salt Lake City, UT 84108
echelon@echelon-inc.com
http://www.echelon-inc.com
headquarters: United States