Active Human Recombinant Alpha Synuclein Protein Monomer (Type 2), 500 µg | Eagle BioSciences SPR-316E product information

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product summary

company name :

Eagle BioSciences

product type :

protein

product name :

Active Human Recombinant Alpha Synuclein Protein Monomer (Type 2), 500 µg

catalog :

SPR-316E

quantity :

500 µg

price :

500.00 USD

product information

Eagle Catalog Number :

SPR-316E

Description :

Active Human Recombinant Alpha Synuclein Protein Monomer (Type 2), 500 µg

Assay Background :

The Active Human Recombinant SNCA Protein Monomer (Type 2) is intended for detection of Alpha Synuclein in Human E. coli.

Assay Principle :

Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson’s disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6).

Product Type :

Protein

Product Category :

Antibody

Size :

500 µg

Species :

Human

Regulatory Status :

RUO

Shipping :

dry ice

Storage :

-80C

LIST Price :

500.00 USD

VWR Price :

$425