Trastuzumab (Herceptin®) ELISA Assay Kit | Eagle BioSciences IG-AB105 product information

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product summary

company name :

Eagle BioSciences

product type :

ELISA/assay

product name :

Trastuzumab (Herceptin®) ELISA Assay Kit

catalog :

IG-AB105

product information

Eagle Catalog Number :

IG-AB105

Description :

Trastuzumab (Herceptin®) ELISA Assay Kit

Assay Background :

The drug Trastuzumab (trade names Herceptin® or Herclon®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). The antibody is an IgG1 kappa that contains human framework regions with the complementarity-determining regions of a murine anti-p185 HER2 antibody that binds to HER2. Trastuzumab blood concentrations throughout the dosing interval expected to be remaining above those considered necessary for anticancer activity. Furthermore, in a separate analysis, patients with the lowest Trastuzumab serum trough concentrations had the highest rate of disease progression and shortest overall survival. This Eagle Biosciences ImmunoGuide Trastuzumab ELISA (mAb-based) is developed for the specific measurement of Trastuzumabin serum, plasma,and other biological fluids by the advantage of using a site-directed VME-5A6b mouse monoclonal antibody (mAb) specific for Trastuzumab only.