product summary
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company name :
Eagle BioSciences
product type :
other
product name :
easYmer HLA-A*01:01 MHC Tetramers Kit, 50 Tests
catalog :
1001-01-50
quantity :
50 Tests
price :
1160 USD
more info or order :
product information
Eagle Catalog Number :
1001-01-50
Description :
easYmer HLA-A*01:01 MHC Tetramers Kit, 50 Tests
Assay Principle :
This protocol is designed to evaluate the efficiency of peptide-HLA-I interaction and complex formation. The assay is based on detecting the ß2-microglobulin (ß2m? light chain subunit of recombinant HLA Class I (HLA-I) comlexes, where the heavy chain has been biotin tagged. These tagged complexes are subsequently captured by streptavidin coated beads, labeled with PE-conjugated anti-human ß2m, and analyzed by flow cytometry. Since peptide-HLA-I complex formation is entirely peptide dependent, bead-associated signals will only be detected if the peptide in question supports the folding of the HLA-I allotype of interest; peptides that efficiently support folding will give strong signals whereas peptides that support folding sub-optimally, or not at all, will give moderate to non-detectable signals.
Product Type :
MHC Tetramers
Product Category :
easYmer
Product Subcategory :
Cancer Biomarkers
Size :
50 Tests
Regulatory Status :
RUO
Shipping :
wet
Storage :
-20C
LIST Price :
1160 USD
more info or order :
company information
Eagle BioSciences
20A NW Blvd., Suite 112
Nashua, NH 03063
Nashua, NH 03063
info@eaglebio.com
http://www.eaglebio.com866-411-8023
headquarters: USA
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