AFP Mouse mAb (1G7) | EMD Millipore ST1673-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

AFP Mouse mAb (1G7)

catalog :

ST1673-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; loading ...; fig 3b	Wu M, Liu S, Gao Y, Bai H, Machairaki V, Li G, et al. Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system. Stem Cell Res. 2018;29:6-14 pubmed publisher
immunocytochemistry; human; 1:500; loading ...; tbl 1	Liu S, Ye Z, Gao Y, He C, Williams D, MOLITERNO A, et al. Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene. Stem Cell Res. 2017;18:57-59 pubmed publisher

product information

Catalog Number :

ST1673-100UG

Category :

Antibodies

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-AFP Mouse mAb (1G7)

Product Type :

Antibodies

Clonality :

Monoclonal

Host Name :

Clone :

1G7

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-AFP Mouse mAb (1G7)

Cross Reactivity :

Human

Background :

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Immunogen :

A recombinant polypeptide corresponding to amino acids of 500-610 human AFP, expressed as a GST fusion protein

Specificity :

Recognizes the ~70-75 kDa AFP protein.

Package Size :

100 ug

Uses :

ELISA, WB, IC

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.