PKD2 Rabbit pAb | EMD Millipore ST1042-50UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PKD2 Rabbit pAb

catalog :

ST1042-50UG

quantity :

50 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; fig 2 western blot; human; fig 1	Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T. Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 2016;291:462-77 pubmed publisher

product information

Catalog Number :

ST1042-50UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-PKD2 Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

25865 (Hu), 101540 (Ms), 292658 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-PKD2 Rabbit pAb

Cross Reactivity :

Human

Background :

Protein kinase D2 (PKD2) is a serine/threonine protein kinase and a member of PKD family, which also includes PKD/PKD1/PKCmu and PKD3/PKCnu. PKDs are a newly identified protein kinase family with structural, enzymological and regulatory properties different from protein kinase C (PKC) family. PKDs participate in the signal transduction pathway and are potential regulators of cell proliferation and apoptosis. They are stimulated by diacyl-glycerol (DAG), and are substrates for classical PKCs like PKCalpha, PKCepsilon and PKCeta. Therefore, PKD stimulation by DAG is partially mediated through PKCs. PKD2 mRNA is widely expressed in human and murine tissue and codes for a ~105 kDa protein. It is stimulated by both phorbol ester and growth factors and is autophosphorylated upon stimulation. PKD2 is predominantly located in the cytoplasm and, as opposed to other members of the PKD family, does not accumulate in the nucleus upon induction.

ALT Names :

AI325941, HSPC187, PKD2, Protein kinase d2, RGD1308054, protein kinase D2

Immunogen :

a synthetic peptide corresponding to amino acids near the C-terminus of human PKD2

Specificity :

Recognizes the ~105 kDa PKD2 protein.

Package Size :

50 ug

Uses :

WB, IP

Storage :

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw.