Nanog Rabbit pAb | EMD Millipore SC1000-50UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nanog Rabbit pAb

catalog :

SC1000-50UG

quantity :

50 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 2c	Navarra A, Musto A, Gargiulo A, Petrosino G, Pierantoni G, Fusco A, et al. Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state. BMC Biol. 2016;14:24 pubmed publisher
western blot; mouse; 1:2000; loading ...; fig 1a	Li Q, Lex R, Chung H, Giovanetti S, Ji Z, Ji H, et al. The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription. J Biol Chem. 2016;291:7171-82 pubmed publisher

product information

Catalog Number :

SC1000-50UG

Category :

Antibodies

Subcategory :

Stem Cell Research

Product Name :

Anti-Nanog Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

79923 (Hu), 71950 (Ms), 414065 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Nanog Rabbit pAb

Cross Reactivity :

Mouse

Background :

Nanog is a newly identified homeodomain gene product that directs propagation of undifferentiated embryonic stem (ES) cells and was named after the mythological Celtic land of the eternal youth, Tir Na Nog. Nanog is present in both mouse and human embryonic stem cells, and lacking in differentiated cells. It is restricted to founder cells from which ES cells can be derived. Nanog is important for maintaining the self-renewing properties of mouse embryonic stem cells and is expressed in the cells of the early embryo that are used to derive embryonic stem cells. Current research suggests that Nanog acts independently of another signal transduction pathway important to maintaining the pluripotency of stem cells, which involves the activation of Stat3.

ALT Names :

ecat4, ENK, Nanog homeobox

Immunogen :

a synthetic peptide corresponding to amino acids within residues 1-50 of mouse Nanog

Specificity :

Recognizes the ~40 kDa Nanog protein.

Package Size :

50 ug

Uses :

WB, IP

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.