PhosphoDetect™ Anti-FAK (pTyr861) Rabbit pAb | EMD Millipore PS1008-100UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PhosphoDetect™ Anti-FAK (pTyr861) Rabbit pAb

catalog :

PS1008-100UL

quantity :

100 uL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

PS1008-100UL

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

PhosphoDetect™ Anti-FAK (pTyr861) Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

5747 (Hu), 14083 (Ms), 25614 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

PhosphoDetect™ Anti-FAK (pTyr861) Rabbit pAb

Cross Reactivity :

Chicken, Human, Mouse

Background :

Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase that plays a key role in maintaining focal adhesion function and cell survival. It is phosphorylated following growth factor or integrin-mediated cell adhesion stimulation. FAK is localized to focal adhesions through its C-terminal focal adhesion targeting (FAT) domain that acts by binding to paxillin and talin that are associated with the cytoplasmic tails of integrins. Phosphorylation of FAK at Tyr861 by Src promotes this interaction between FAK and integrins.

ALT Names :

FADK, FAK, FAK related non-kinase, FAK1, FOCAL ADHESION KINASE, FRNK, KIAA4203, mKIAA4203, p125FAK, PP125FAK, TYROSINE KINASE 2, PTK2 protein tyrosine kinase 2

Immunogen :

a synthetic phosphopeptide surrounding the Tyr 861 phosphorylation site of human FAK

Specificity :

Recognizes the ~125 kDa FAK protein phosphorylated at Tyr 861 .

Package Size :

100 uL

Uses :

WB, IH

Storage :

Following initial thaw, aliquot and freeze (-20°C). Avoid repeated freeze-thaw.