PTP, T Cell (Ab-1) Mouse mAb (CF4-1D) | EMD Millipore PH03L-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PTP, T Cell (Ab-1) Mouse mAb (CF4-1D)

catalog :

PH03L-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

PH03L-100UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-PTP, T Cell (Ab-1) Mouse mAb (CF4-1D)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

5771 (Hu), 19255 (Ms), 117063 (Rt)

Host Name :

Clone :

CF4-1D

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-PTP, T Cell (Ab-1) Mouse mAb (CF4-1D)

Cross Reactivity :

Human

Background :

Protein tyrosine phosphatases (PTPases) make up an expanding family of transmembrane and intracellular proteins, which function to remove phosphate groups from protein phosphoryl- tyrosine residues. The prototype phosphatase, PTPase 1B, was initially identified as an active intracellular phosphatase from human placenta made up of 321 amino acids and subsequently shown to derive from a larger precursor protein containing 435 amino acids. Using probes to the conserved PTPase domain a cDNA clone was isolated from a human peripheral T cell library encoding a protein with 65% identity to the placental PTPase 1B. The T cell protein differs in amino acid composition but is highly similar with respect to hydrophobicity with the 1B protein and is now known to be present in other cell types. While the function of the T cell PTPase protein is still unknown, recent experiments demonstrated that a truncated form overexpressed in BHK cells resulted in a greatly reduced growth rate of the cells.

ALT Names :

AI325124, PTN2, PTPase, Ptps, PTPT, T CELL PTPASE, TC-PTP, Tc45, TCELLPTP, protein tyrosine phosphatase, non-receptor type 2

Immunogen :

recombinant, human T cell PTPase

Specificity :

Recognizes the PTPase protein.

Package Size :

100 ug

Uses :

WB, IC, IP

Storage :

Reconstitute the lyophilized antibody with sterile PBS, pH 7.4, or sterile 20 mM Tris-saline (20 mM Tris containing 0.15 M NaCl), pH 7.4 to yield a final concentration of 100 ug/ml. Lyophilized antibodies should be resuspended at 4°C with occasional gentle mixing for at least 2 h. Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) with 0.1% azide for short-term storage. Avoid freeze/thaw cycles of solutions. Do not freeze.