Bcl-xL (Ab-1) (201-216) Rabbit pAb | EMD Millipore PC67-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Bcl-xL (Ab-1) (201-216) Rabbit pAb

catalog :

PC67-100UG

quantity :

100 ug

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

PC67-100UG

Category :

Antibodies

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Bcl-xL (Ab-1) (201-216) Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

598 (Hu), 12048 (Ms), 24888 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Bcl-xL (Ab-1) (201-216) Rabbit pAb

Cross Reactivity :

Human, Mouse, Opossum, Rat

Background :

bcl-x is a bcl-2-related gene that can function as a regulator of programmed cell death (apoptosis) independent of bcl-2. Alternative splicing results in two distinct bcl-x mRNAs, bcl-xL and bcl-xS. The larger mRNA gives rise to a protein product, bcl-xL, which is similar in size and predicted structure to bcl-2. bcl-x immunoreactivity has been detected in a wide variety of cell types and the protein is typically present in the cytosol in association with the mitochondrial periphery, a property shared with bcl-2. Of the two isoforms of bcl-x, the long (bcl-xL) is the most abundant mRNA species expressed in embryonic and adult tissues and most likely differs from bcl-2 in its regulatory activity on cell differentiation through controlled tissue specific expression. Like its homolog bcl-2, the mechanism and extent of bcl-x's function are still increasing.

ALT Names :

bBclxl, Bcl(X)L, BCL-2, Bcl-X beta, Bcl-x(L), BCL-XL/S, BCL-XS, BCL2L, BCLX, Bclx gamma, DKFZp781P2092, MGC113803, MGC99998, BCL2-like 1

Immunogen :

a synthetic peptide (PWIQENGGWDTFVELY) corresponding to amino acids 201-216 of human Bcl-x

Specificity :

Recognizes the ~28 kDa Bcl-x protein.

Package Size :

100 ug

Uses :

IH, WB, IH(P)

Storage :

Do not freeze