This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Rad51 (Ab-1) Rabbit pAb
catalog :
PC130
clonality :
polyclonal
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 34
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2c
Daddacha W, Koyen A, Bastien A, Head P, Dhere V, Nabeta G, et al. SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. Cell Rep. 2017;20:1921-1935 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 2a
Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2b
Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s5b
Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 2
Li M, Cole F, Patel D, Misenko S, Her J, Malhowski A, et al. 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. EMBO Rep. 2016;17:1532-1541 pubmed
  • immunocytochemistry; human; loading ...; fig 3d
Bakr A, Köcher S, Volquardsen J, Petersen C, Borgmann K, Dikomey E, et al. Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1. Oncotarget. 2016;7:57679-57693 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 7
Gygli P, Chang J, Gokozan H, Catacutan F, Schmidt T, Kaya B, et al. Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging (Albany NY). 2016;8:1540-70 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 5
Penterling C, Drexler G, Böhland C, Stamp R, Wilke C, Braselmann H, et al. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair. PLoS ONE. 2016;11:e0156599 pubmed publisher
  • western blot; mouse; 1:2500; loading ...; fig s9a
Jaber S, Toufektchan E, Lejour V, Bardot B, Toledo F. p53 downregulates the Fanconi anaemia DNA repair pathway. Nat Commun. 2016;7:11091 pubmed publisher
  • immunocytochemistry; human; fig s1
Renaud E, Barascu A, Rosselli F. Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res. 2016;44:648-56 pubmed publisher
Tsai L, Lopezcolorado F, Bhargava R, Mendez Dorantes C, Jahanshir E, Stark J. RNF8 has both KU-dependent and independent roles in chromosomal break repair. Nucleic Acids Res. 2020;48:6032-6052 pubmed publisher
Kojima Y, Machida Y, Palani S, Caulfield T, Radisky E, Kaufmann S, et al. FAM111A protects replication forks from protein obstacles via its trypsin-like domain. Nat Commun. 2020;11:1318 pubmed publisher
Li Y, Tong K, Lu J, Lin J, Li Z, Sang Y, et al. PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. Aging (Albany NY). 2020;12:2507-2529 pubmed publisher
Abe H, Alavattam K, Hu Y, Pang Q, Andreassen P, Hegde R, et al. The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis. Curr Biol. 2019;: pubmed publisher
Rossi F, Helbling Leclerc A, Kawasumi R, Jegadesan N, Xu X, Devulder P, et al. SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. EMBO Rep. 2019;:e48222 pubmed publisher
Kanakkanthara A, Huntoon C, Hou X, Zhang M, Heinzen E, O Brien D, et al. ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer. Nat Commun. 2019;10:4632 pubmed publisher
Burrage L, Reynolds J, Baratang N, Phillips J, Wegner J, McFarquhar A, et al. Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. Am J Hum Genet. 2019;104:422-438 pubmed publisher
Hirota T, Blakeley P, Sangrithi M, Mahadevaiah S, Encheva V, Snijders A, et al. SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. Dev Cell. 2018;47:645-659.e6 pubmed publisher
Abreu C, Prakash R, Romanienko P, Roig I, Keeney S, Jasin M. Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun. 2018;9:3961 pubmed publisher
Sulkowski P, Sundaram R, Oeck S, Corso C, Liu Y, Noorbakhsh S, et al. Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. Nat Genet. 2018;50:1086-1092 pubmed publisher
Widger A, Mahadevaiah S, Lange J, Elinati E, Zohren J, Hirota T, et al. ATR is a multifunctional regulator of male mouse meiosis. Nat Commun. 2018;9:2621 pubmed publisher
Higgs M, Sato K, Reynolds J, Begum S, Bayley R, Goula A, et al. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Mol Cell. 2018;71:25-41.e6 pubmed publisher
Sun C, Yin J, Fang Y, Chen J, Jeong K, Chen X, et al. BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency. Cancer Cell. 2018;33:401-416.e8 pubmed publisher
Mansour W, Tennstedt P, Volquardsen J, Oing C, Kluth M, Hube Magg C, et al. Loss of PTEN-assisted G2/M checkpoint impedes homologous recombination repair and enhances radio-curability and PARP inhibitor treatment response in prostate cancer. Sci Rep. 2018;8:3947 pubmed publisher
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton S. Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell. 2018;172:439-453.e14 pubmed publisher
Thompson E, Yeo J, Lee E, Kan Y, Raghunandan M, Wiek C, et al. FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. Nucleic Acids Res. 2017;45:11837-11857 pubmed publisher
Hollingworth R, Horniblow R, Forrest C, Stewart G, Grand R. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2017;91: pubmed publisher
Li Y, Sun H, Zhang C, Zhang H, Fan F, Everley R, et al. Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics. Oncogene. 2017;36:6839-6849 pubmed publisher
King H, Brend T, Payne H, Wright A, Ward T, Patel K, et al. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports. 2017;8:125-139 pubmed publisher
Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock C, Li C, et al. Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors. elife. 2016;5: pubmed publisher
Mayer M, Kaiser N, Layer P, Frohns F. Cell Cycle Regulation and Apoptotic Responses of the Embryonic Chick Retina by Ionizing Radiation. PLoS ONE. 2016;11:e0155093 pubmed publisher
Byrd P, Stewart G, Smith A, Eaton C, Taylor A, Guy C, et al. A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development. PLoS Genet. 2016;12:e1005945 pubmed publisher
Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed publisher
Kao G, McKenna W, Guenther M, Muschel R, Lazar M, Yen T. Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. J Cell Biol. 2003;160:1017-27 pubmed
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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