PTHLP (Ab-2) (34-53) Rabbit pAb | EMD Millipore PC09-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PTHLP (Ab-2) (34-53) Rabbit pAb

catalog :

PC09-100UG

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

PC09-100UG

Category :

Antibodies

Subcategory :

Neuroscience

Product Name :

Anti-PTHLP (Ab-2) (34-53) Rabbit pAb

Product Type :

Antibodies

Clonality :

Polyclonal

Gene ID :

5744 (Hu), 19227 (Ms), 24695 (Rt)

Host Name :

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-PTHLP (Ab-2) (34-53) Rabbit pAb

Cross Reactivity :

Human

Background :

Parathyroid Hormone-Like Protein (PTHLP; also called Parathyroid Hormone-related Protein or PTHrP) is a polypeptide factor implicated in a severe neoplastic syndrome, Humoral Hypercalcemia of Malignancy, that is most commonly associated with renal cell and squamous cell carcinomas. It has been purified from tumors of patients with this syndrome and also from the conditioned medium of human tumor cell lines. Oligonucleotide probes, based upon the amino-terminal sequence of PTHLP, have been used to clone several cDNAs corresponding to alternatively spliced mRNAs that are both encoded by a single gene. Homogeneous recombinant PTHLP (141 amino acids) as well as synthetic peptides corresponding to the amino-terminal region of the protein have in vitro and in vivo biological activities as expected for a factor involved with calcium homeostasis.

ALT Names :

HHM, MGC14611, parathyroid hormone-like hormone A, PARATHYROID HORMONE-RELATED PROTEIN PRECURSOR, PLP, PTH-like, PTHR, PTHRP, parathyroid hormone-like hormone

Immunogen :

a synthetic peptide (AEIRATSEVSPNSKPSPNTK) corresponding to amino acids 34-53 of human PTHLP

Specificity :

Recognizes parathyroid hormone-like protein (PTHLP).

Package Size :

100 ug

Uses :

FC, WB, IF, IP, IH(P)

Storage :

Do not freeze