This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
BRCA2
catalog :
OP95
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B
reactivity :
human
application :
western blot
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 8d
Singh A, Oehler J, Torrecilla I, Kilgas S, Li S, Vaz B, et al. The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8. EMBO J. 2019;38:e102361 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
Reisländer T, Lombardi E, Groelly F, Miar A, Porru M, Di Vito S, et al. BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors. Nat Commun. 2019;10:3143 pubmed publisher
  • western blot; human; 1:1000; fig 3a
Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed publisher
  • western blot; human; loading ...; fig s7b
Wang J, Chan B, Tong M, Paung Y, Jo U, MARTIN D, et al. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway. PLoS Genet. 2019;15:e1007983 pubmed publisher
  • western blot; human; 1:200; fig 4d
Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis N, et al. Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol. 2018;19:37 pubmed publisher
  • western blot; human; 1:1000; fig 2b
Bleuyard J, Fournier M, Nakato R, Couturier A, Katou Y, Ralf C, et al. MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress. Proc Natl Acad Sci U S A. 2017;114:7671-7676 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig s2a
Tan S, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, et al. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability. Cell. 2017;169:1105-1118.e15 pubmed publisher
  • western blot; human; fig 2b
Gilmore B, Liang Y, Winton C, Patel K, Karageorge V, Varano A, et al. Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress. Sci Rep. 2017;7:43435 pubmed publisher
  • western blot; human; fig 1d
Wilkerson P, Dedes K, Samartzis E, Dedes I, Lambros M, Natrajan R, et al. Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer. Oncotarget. 2017;8:6057-6066 pubmed publisher
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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