APC (Ab-7) Mouse mAb (CC-1) | EMD Millipore OP80-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

APC (Ab-7) Mouse mAb (CC-1)

catalog :

OP80-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry - free floating section

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3h	Garcia Agudo L, Janova H, Sendler L, Arinrad S, Steixner A, Hassouna I, et al. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. FASEB J. 2019;33:8634-8647 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 2e	Lischinsky J, Sokolowski K, Li P, Esumi S, Kamal Y, Goodrich M, et al. Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues. elife. 2017;6: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50; fig 8	Rolyan H, Tyurina Y, Hernandez M, Amoscato A, Sparvero L, Nmezi B, et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015;35:12002-17 pubmed publisher
immunohistochemistry; mouse; 1:50	Kraushar M, Viljetić B, Wijeratne H, Thompson K, Jiao X, Pike J, et al. Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci. 2015;35:10911-26 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:400	Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, et al. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Mol Neurobiol. 2016;53:3235-3248 pubmed publisher
immunohistochemistry - frozen section; rat; 1:400	Steward O, Sharp K, Yee K, Hatch M, Bonner J. Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury. J Neurosci. 2014;34:14013-21 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50	Lin Y, Pang X, Huang G, Jamison S, Fang J, Harding H, et al. Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. J Neurosci. 2014;34:12182-91 pubmed publisher
immunohistochemistry - frozen section; rat; 1:400	Sharp K, Yee K, Steward O. A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury. Exp Neurol. 2014;257:186-204 pubmed publisher
immunohistochemistry - frozen section; rat; 1:200	Sevc J, Matiašová A, Kútna V, Daxnerova Z. Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats. J Comp Neurol. 2014;522:3194-207 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200	Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, et al. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis. Hum Mol Genet. 2014;23:668-81 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:40 immunocytochemistry; mouse; 1:200	Chen C, Sloane J, Li H, Aytan N, Giannaris E, Zeldich E, et al. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013;33:1927-39 pubmed publisher
	Dent K, Christie K, Bye N, Basrai H, Turbic A, Habgood M, et al. Oligodendrocyte birth and death following traumatic brain injury in adult mice. PLoS ONE. 2015;10:e0121541 pubmed publisher

product information

Catalog Number :

OP80-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-APC (Ab-7) Mouse mAb (CC-1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

324 (Hu), 11789 (Ms), 24205 (Rt)

Host Name :

Clone :

CC-1

Conjugate :

Purified

Isotype :

IgG2b

Product Description :

Anti-APC (Ab-7) Mouse mAb (CC-1)

Cross Reactivity :

Human, Mouse, Rat

Background :

Germ line mutations in the APC gene are responsible for familial adenomatous polyposis and somatic mutations contribute to sporadic colorectal cancer. The 312 kDa APC protein is expressed in all tissues and localized to the cytoskeletal architecture in an insoluble complex with beta-catenin. The APC (Ab-7) mouse monoclonal antibody clone CC-1 decorates oligodendrocyte cell bodies, purkinje cells, astrocytes, and optic nerve cell bodies of formalin-fixed, paraffin-embedded, or fresh frozen sections from human, mouse, and rat brain. Dectection of APC (Ab-7) can be perfomed using immunofluorescence or immunohistochemistry techniques.

ALT Names :

AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC, adenomatous polyposis coli

Immunogen :

a recombinant protein consisting of amino acids 1-226 of APC

Specificity :

Recognizes the ~312 kDa APC protein.

Package Size :

100 ug

Uses :

IH, IH, IC, IF, IH(P)

Storage :

Do not freeze