Rb (Ab-5) Mouse mAb (LM95.1) | EMD Millipore OP66-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rb (Ab-5) Mouse mAb (LM95.1)

catalog :

OP66-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

OP66-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Rb (Ab-5) Mouse mAb (LM95.1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

5925 (Hu), 19645 (Ms), 24708 (Rt)

Host Name :

Clone :

LM95.1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-Rb (Ab-5) Mouse mAb (LM95.1)

Cross Reactivity :

Human

Background :

Certain genes have been identified whose function appears to be the supression of tumor formation and are therefore classified as tumor suppressor genes. One such gene has been linked to the hereditary cancer retinoblastoma. The retino-blastoma (Rb) gene encodes a protein of 928 amino acids which is found predominantly in the nucleus and has the capability of binding to DNA. The Rb protein may be modified by phosphorylation but while there are several potential sites for N-linked glycosylation, no modification has been detected. The Rb protein has been reported as having apparent molecular weights of ~105 kDa, ~100-114 kDa, and ~102 or ~104 kDa which are antigenically related. The Rb protein has been detect in at least 20 different common laboratory cell lines with the exception of retinoblastoma cells.

ALT Names :

OSRC, p105, p105-Rb, p110 RB, pp110, PRB, RB, RB-ASSOCIATED, RETINOBLASTOMA, retinoblastoma 1

Immunogen :

recombinant, human Rb

Specificity :

Recognizes the ~105 kDa Rb protein.

Package Size :

100 ug

Uses :

WB, IH(P)

Storage :

Do not freeze