c-Myc (Ab-3) Mouse mAb (33) | EMD Millipore OP31-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-Myc (Ab-3) Mouse mAb (33)

catalog :

OP31-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

OP31-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-c-Myc (Ab-3) Mouse mAb (33)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

4609 (Hu), 17869 (Ms), 24577 (Rt)

Host Name :

Clone :

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-c-Myc (Ab-3) Mouse mAb (33)

Cross Reactivity :

Avian, Human, Mouse

Background :

The v-myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans the family consists of five genes: c-myc, N-myc, R-myc, L-myc and B-myc. In both mouse plasmacytomas and human Burkitt's lymphoma, coding sequences from the c-myc gene are translocated from their normal chromosomal position into a transcriptionally active immunoglobulin locus on another chromosome. Amplification of the c-myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-myc gene has been found amplified in neuroblastomas, small cell lung carcinomas and Wilms tumors. L-myc is amplified in small cell lung cancer. Furthermore, elevated levels of myc mRNA and protein have been demonstrated in human tumors even in the absence of gene amplification.

ALT Names :

AU016757, bHLHe39, C-MYC, C-MYC-P64, MGC105490, MGC138120, mMyc, MRTL, Myc2, Niard, Nird, RNCMYC, v-myc myelocytomatosis viral oncogene homolog (avian)

Immunogen :

recombinant, human c-Myc

Specificity :

Recognizes the ~60-67 kDa (apparent MW) c-Myc protein.

Package Size :

100 ug

Uses :

IH, WB, IF, IP

Storage :

Do not freeze