c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1) | EMD Millipore OP23-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1)

catalog :

OP23-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; loading ...; fig 2b	Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher

product information

Catalog Number :

OP23-100UG

Category :

Antibodies

Subcategory :

Cell Signaling

Product Name :

Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

3265 (Hu), 15461 (Ms), 293621 (Rt)

Host Name :

Clone :

F235-1.7.1

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1)

Cross Reactivity :

Human, Mouse, Rat

Background :

The human ras gene family consists of three identified members, H, K and N-ras, encoding proteins of 188-189 amino acids and 21,000 (p21) molecular weight. Human H- and K-Ras are the homologues of v-H- and v-K-Ras sequences originally isolated from Harvey and Kirsten strains of rat sarcoma viruses. Normal human cellular ras genes can be activated to oncogenes by mutations occurring in codons 12, 13 and 61; such mutated, activated and transforming ras genes have been identified and isolated from human tumors and cultured tumor cells. Although the expression patterns of Ras proteins in normal human tissues are known, similar information for activated ras oncogene encoded p21's and their relevance to human disease diagnosis and prognosis is still emerging.

ALT Names :

C-BAS/HAS, C-H-RAS, C-HA-RAS, C-HA-RAS-1, c-rasHa, CTLO, H-RASIDX, HA-RAS, HAMSV, Harvey-ras, Hras1, Kras2, N-RAS, RAS, RAS HA, RASH1, V-H-RAS, v-Ha-ras Harvey rat sarcoma viral oncogene homolog

Immunogen :

recombinant p21 Ras

Specificity :

Recognizes the ~21 kDa c-H-Ras protein.

Package Size :

100 ug

Uses :

IH, WB, IF, IP, IH(P)

Storage :

Do not freeze