c-Myc (Ab-1) Mouse mAb (9E10) Fluorescein Conjugate | EMD Millipore OP10F-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-Myc (Ab-1) Mouse mAb (9E10) Fluorescein Conjugate

catalog :

OP10F-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunocytochemistry, flow cytometry

product information

Catalog Number :

OP10F-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-c-Myc (Ab-1) Mouse mAb (9E10) Fluorescein Conjugate

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

4609 (Hu), 17869 (Ms), 24577 (Rt)

Host Name :

Clone :

9E10

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-c-Myc (Ab-1) Mouse mAb (9E10) Fluorescein Conjugate

Cross Reactivity :

Human, Mouse (weakly), Rat (weakly)

Background :

The v-myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans the family consists of five genes: c-myc, N-myc, R-myc, L-myc, and B-myc. Amplification of the c-myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-myc gene has been found amplified in neuroblastomas, small cell lung carcinomas and Wilms tumors. L-myc is amplified in small cell lung cancer. Immunological studies have shown that the human c-myc gene gives rise to at least two nuclear phosphoproteins of ~64 kDa and ~67 kDa that exhibit relatively short (30 min) half lives in vivo and exhibit DNA binding properties in vitro.

ALT Names :

AU016757, bHLHe39, C-MYC, C-MYC-P64, MGC105490, MGC138120, mMyc, MRTL, Myc2, Niard, Nird, RNCMYC, v-myc myelocytomatosis viral oncogene homolog (avian)

Immunogen :

a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc

Specificity :

Recognizes the ~64-67 kDa (apparent MW) c-Myc protein.

Package Size :

100 ug

Uses :

FC, IF

Storage :

Do not freeze. Protect from light.