v-Src (Ab-1) Mouse mAb (327) | EMD Millipore OP07L-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

v-Src (Ab-1) Mouse mAb (327)

catalog :

OP07L-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig s3	HÃ¸ye A, Couchman J, Wewer U, Yoneda A. The Phosphorylation and Distribution of Cortactin Downstream of Integrin Î±9Î²1 Affects Cancer Cell Behaviour. Sci Rep. 2016;6:28529 pubmed publisher
western blot; human	Richter E, Harms M, Ventz K, Gierok P, Chilukoti R, Hildebrandt J, et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS ONE. 2015;10:e0122089 pubmed publisher

product information

Catalog Number :

OP07L-100UG

Category :

Antibodies

Subcategory :

Cell Structure

Product Name :

Anti-v-Src (Ab-1) Mouse mAb (327)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

6714 (Hu), 20779 (Ms), 83805 (Rt)

Host Name :

Clone :

327

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-v-Src (Ab-1) Mouse mAb (327)

Cross Reactivity :

Human, Mouse, Rat

Background :

The major translational product of the avian sarcoma virus has been designated pp60src. Avian sarcoma virus pp60src possesses a characteristic protein kinase activity with specificity for tyrosine residues. The mammalian cellular homologue of pp60src, designated pp60c-src, exhibits a similar protein tyrosine kinase activity which can be activated by interaction with polyoma virus-encoded middle T antigen. Immunoprecipitates of middle T antigen also contain phosphatidylinositol kinase activity coinciding with the presence of a 81 kDa (p81) protein. The p81 is phosphorylated by activated pp60c-src and is thought to be the phosphatidylinositol kinase.

ALT Names :

ASV, AW259666, C-SRC, NSRC, p60 SRC, p60v-Src, PP60, PP60 SRC, Pp60/c-Src, PP60C-SRC, SRC1, TVHUSC, V-SRC, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Immunogen :

purified v-Src

Specificity :

Recognizes the ~60 kDa Src protein.

Package Size :

100 ug

Uses :

WB, IP

Storage :

Reconstitute the lyophilized antibody with sterile PBS, pH 7.4, or sterile 20 mM Tris-saline, pH 7.4, to yield a final concentration of 100 ug/ml. Following reconstitution, refrigerate (4°C) with 0.1% azide for short-term storage or aliquot and freeze (-20°C) for long-term storage. Avoid repeated freeze/thaw cycles of solutions. Lyophilized antibodies should be reconstituted at 4°C with occasional gentle mixing for at least 2 h.