p27kip-1 (Ab-2) Mouse mAb (DCS72) | EMD Millipore NA35-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

p27kip-1 (Ab-2) Mouse mAb (DCS72)

catalog :

NA35-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

NA35-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-p27kip-1 (Ab-2) Mouse mAb (DCS72)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

1027 (Hu), 12576 (Ms), 83571 (Rt)

Host Name :

Clone :

DCS72

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-p27kip-1 (Ab-2) Mouse mAb (DCS72)

Cross Reactivity :

Human, Mouse

Background :

p27, the product of the p27Kip1 gene, is an inducible inhibitor of cyclin dependent kinase activity. Related to p21WAF, p27 interacts strongly with D-type cyclins in complex with cdk4 and more weakly with cyclin E and cdk2 complexes2. Based on results from experiments in which p27 is overexpressed in cell lines, it appears that p27 acts as a negative regulator of G1 progression, and in fact, increased levels of the protein have been observed in cells undergoing G1 arrest following treatment with TGFbeta. The p27 gene has been localized to chromosome 12p13.

ALT Names :

AA408329, AI843786, Cdki1b, CDKN4, CYCLIN-DEPENDENT KINASE INHIBITOR P27, KIP1, MEN1B, MEN4, P27, P27kip, P27KIP1, P28-ICK, cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Immunogen :

recombinant p27 Kip-1

Specificity :

Recognizes the ~27 kDa p27 kip-1 protein.

Package Size :

100 ug

Uses :

WB, IH(P)

Storage :

Do not freeze