MSH2 (Ab-2) Mouse mAb (FE11) | EMD Millipore NA27-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MSH2 (Ab-2) Mouse mAb (FE11)

catalog :

NA27-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100; fig s4b	Beltran H, Prandi D, Mosquera J, Benelli M, Puca L, Cyrta J, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016;22:298-305 pubmed publisher

product information

Catalog Number :

NA27-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-MSH2 (Ab-2) Mouse mAb (FE11)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

4436 (Hu), 17685 (Ms), 81709 (Rt)

Host Name :

Clone :

FE11

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-MSH2 (Ab-2) Mouse mAb (FE11)

Cross Reactivity :

Human, Mouse

Background :

The MSH2 gene is one of at least 4 genes encoding proteins involved in the repair of mismatch nucleotides following DNA replication or repair. Mutations in the MSH2 gene contribute to the development of sporadic colorectal carcinoma, while germline MSH2 mutations are responsible for ~50% of inherited, non-polyposis colorectal carcinoma (HNPCC). MSH2 encodes a protein of 934 amino acids.

ALT Names :

AI788990, COCA1, FCC1, HNPCC, HNPCC1, LCFS2, mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

Immunogen :

a C-terminal fragment of human MSH2

Specificity :

Recognizes the ~100 kDa MSH2 protein.

Package Size :

100 ug

Uses :

IH, WB, IP, IH(P)

Storage :

Do not freeze