Replication Protein A (Ab-1) Mouse mAb (RPA70-9) | EMD Millipore NA13-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Replication Protein A (Ab-1) Mouse mAb (RPA70-9)

catalog :

NA13-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; fig 1 western blot; human; 1:1000; fig 1	Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher

product information

Catalog Number :

NA13-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Replication Protein A (Ab-1) Mouse mAb (RPA70-9)

Product Type :

Antibodies

Clonality :

Monoclonal

Gene ID :

6117 (Hu), 68275 (Ms), 287524 (Rt)

Host Name :

Clone :

RPA70-9

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Replication Protein A (Ab-1) Mouse mAb (RPA70-9)

Cross Reactivity :

Human, Yeast

Background :

The replication system of a cell contains several essential components among which are replication factor A (RFA, RPA, or HeLa cell SSB), PCNA, and replication factor C (RFC) as well as several other proteins. RPA, a multi-subunit protein containing a 70 kDa, 34 kDa, and 11 kDa protein, may play a critical regulatory role in replication based on its functioning during both the initiation and elongation stages of DNA replication. The protein is highly conserved, having been identified in a range of species from yeast (Saccharomyces cerevisiae) to humans. The primary function of RPA appears to be as an auxiliary protein for both DNA polymerase alpha and Δ. RPA undergoes a cell cycle dependent phosphorylation, which is restricted to the p34 protein. In addition to existing as part of the multi-subunit structure, p34 has also been identified as being present in a free, unphosphorylated form.

ALT Names :

5031405K23Rik, 70kDa, AA589576, AW557552, Cb1-727, HSSB, MST075, p70Rpa1, REPA1, Replication Factor 1a, RF-A, RP-A, RPA32, RPA70, replication protein A1, 70kDa

Immunogen :

replication protein A purified from U293 cells

Specificity :

Recognizes the ~70 kDa Replication Protein A.

Package Size :

100 ug

Uses :

IH, WB, IF, IP, IH(P)

Storage :

Do not freeze