2,2,7-Trimethylguanosine Mouse mAb (K121) | EMD Millipore NA02-100UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

2,2,7-Trimethylguanosine Mouse mAb (K121)

catalog :

NA02-100UG

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

NA02-100UG

Category :

Antibodies

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-2,2,7-Trimethylguanosine Mouse mAb (K121)

Product Type :

Antibodies

Clonality :

Monoclonal

Host Name :

Clone :

K121

Conjugate :

Purified

Isotype :

IgG1

Product Description :

Anti-2,2,7-Trimethylguanosine Mouse mAb (K121)

Cross Reactivity :

Human, Mouse, Rat

Background :

The U small nuclear ribonucleoprotein particles (snRNPs) are present in all eukaryotes studied thus far and are involved in the splicing of RNA molecules. snRNPs are composed of several proteins and one or two RNA molecules. The RNA molecules (snRNAs) contain a unique 5' terminal cap structure containing the nucleoside 2,2,7-trimethylguanosine. The 70 kDa protein component of U1 snRNP is cleaved during apoptosis, perhaps by a caspase. Monoclonal antibodies to the 5' cap structure react only to snRNAs.

ALT Names :

2, 2, 7-Trimethylguanosine Mouse mAb (K121)

Immunogen :

2,2,7-trimethylguanosine

Specificity :

Recognizes the exposed 5ʹ cap structure (2,2,7-trimethylguanosine) of small nuclear RNAs (snRNAs).

Package Size :

100 ug

Uses :

IC, IP, IH(P)

Storage :

Do not freeze