Arp2/3 complex Antibody, clone 13C9 | EMD Millipore MABT95 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Arp2/3 complex Antibody, clone 13C9

catalog :

MABT95

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13C9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; loading ...; fig 5a	Barger S, Reilly N, Shutova M, Li Q, Maiuri P, Heddleston J, et al. Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis. Nat Commun. 2019;10:1249 pubmed publisher
immunohistochemistry - paraffin section; human; 1:2500; loading ...; fig s11	Frentzas S, Simoneau E, Bridgeman V, Vermeulen P, Foo S, Kostaras E, et al. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016;22:1294-1302 pubmed publisher
western blot; rat; 1:500; fig 4	Kim A, Zamora Martinez E, Edwards S, Mandyam C. Structural reorganization of pyramidal neurons in the medial prefrontal cortex of alcohol dependent rats is associated with altered glial plasticity. Brain Struct Funct. 2015;220:1705-20 pubmed publisher

product information

Catalog Number :

MABT95

Subcategory :

Cell Structure

Product Name :

Anti-Arp2/3 complex Antibody, clone 13C9

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O15145

Host Name :

Mouse

Antigen :

Arp2/3 complex

Clone :

13C9

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Arp2/3 complex Antibody, clone 13C9

Cross Reactivity :

Human

Background :

The Arp2/3 complex, which contains ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC, plays a major role in the regulation of the actin polymerization in the cytoskeleton. Two of complex's seven subunits (ARP2 and ARP3) closely resemble monomeric actin and serve as nucleation sites for new actin filaments. The Arp2/3 complex works in conjunction with an activating nucleation-promoting factor (NPF) to aid in the formation of branched actin networks. The regulation of actin cytoskeleton reorganization is important for processes like cell migration, phagocytosis, and intracellular motility of lipid vesicles.

ALT Names :

Actin-related protein 2/3 complex subunit 3;Arp2/3 complex 21 kDa subunit;p21-ARC

Immunogen :

GST-tagged recombinant protein corresponding to human Arp2/3 complex.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt