Aggrecan Antibody, clone 1-C-6 | EMD Millipore MABT84 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Aggrecan Antibody, clone 1-C-6

catalog :

MABT84

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1-C-6

reactivity :

mouse, rat, bovine

application :

western blot, immunohistochemistry

citations: 2

Reference
Whitaker A, Berthet E, Cantu A, Laird D, Alliston T. Smad4 regulates growth plate matrix production and chondrocyte polarity. Biol Open. 2017;6:358-364 pubmed publisher
Poon C, Plaas A, Keene D, McQuillan D, Last K, Fosang A. N-linked keratan sulfate in the aggrecan interglobular domain potentiates aggrecanase activity. J Biol Chem. 2005;280:23615-21 pubmed

product information

Catalog Number :

MABT84

Subcategory :

Cell Structure

Product Name :

Anti-Aggrecan Antibody, clone 1-C-6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P07897

Host Name :

Mouse

Antigen :

Aggrecan

Clone :

1-C-6

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Aggrecan Antibody, clone 1-C-6

Cross Reactivity :

Rat;Mouse;Bovine

Background :

Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight.

ALT Names :

Aggrecan core protein;Cartilage-specific proteoglycan core protein;CSPCP

Immunogen :

Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma

Package Size :

100 μg

Uses :

Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt