Nectin-1/PVRL1 (CD111) Antibody, clone R1.302 | EMD Millipore MABT61 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nectin-1/PVRL1 (CD111) Antibody, clone R1.302

catalog :

MABT61

quantity :

50 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

R1.302.12

The same clone is also sold as:

Santa Cruz Biotechnology: sc-69718

reactivity :

human

application :

immunocytochemistry, flow cytometry

citations: 1

Reference
Boylan K, Buchanan P, Manion R, Shukla D, Braumberger K, Bruggemeyer C, et al. The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate. Oncotarget. 2017;8:9717-9738 pubmed publisher

product information

Catalog Number :

MABT61

Subcategory :

Cell Structure

Product Name :

Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q15223

Host Name :

Mouse

Antigen :

Nectin-1/PVRL1 (CD111)

Clone :

R1.302.12

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302

Cross Reactivity :

Human

Background :

Nectin-1, also known as poliovirus receptor-related protein 1 (PRR1 or PVRL1) or CD111, is an immunoglobulin-like transmembrane cell adhesion protein that also seems to play a role in neural tube formation, with N-cadherin. Nectins are known for being the receptors for the herpes simplex virus. Nectin-1 is connected with the actin cytoskeleton through afadin inside the cell. It is predominantly found in human placenta although in mice, expression is wide-ranging. Nectin-1 seems to adhere primarily to cells expressing nectin-4 and vice versa.

ALT Names :

poliovirus receptor-related 1 (herpesvirus entry mediator C);nectin-1;poliovirus receptor-related protein 1;poliovirus receptor-like 1;nectin 1;ectodermal dysplasia 4 (Margarita Island type);Herpesvirus entry mediator C;Herpes virus entry mediator C;Nectin-1;Herpesvirus Ig-like receptor;CD111 antigen

Immunogen :

Human CD111 transfected NIH/3T3 cells

Package Size :

50 μg

Uses :

Flow Cytometry;Immunofluorescence

Storage :

Stable for 1 year at 2-8°C from date of receipt