Moesin Antibody, clone 38/87 | EMD Millipore MABT414 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Moesin Antibody, clone 38/87

catalog :

MABT414

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

38/87

The same clone is also sold as:

Santa Cruz Biotechnology: sc-58806
LifeSpan Biosciences: LS-B8628
MilliporeSigma: M7060
Invitrogen: MA5-14043

reactivity :

human, bovine

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

Catalog Number :

MABT414

Subcategory :

Cell Structure

Product Name :

Anti-Moesin Antibody, clone 38/87

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q2HJ49

Host Name :

Mouse

Antigen :

Moesin

Clone :

38/87

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Moesin Antibody, clone 38/87

Cross Reactivity :

Human;Bovine

Background :

Moesin (membrane-organizing extension spike protein) is the protein encoded by the MSN gene. Moesin is a member of the ERM (ezrin, moesin, radixin) family of proteins that regulate linkage between the plasma membrane and the actin cytoskeleton. Thus, moesin is a peripheral membrane protein that is keenly involved in the signaling and structural connections in cytoskeletal plasma membrane structures like microvilli. Moesin in its active, phosphorylated state strongly binds actin and helps anchor it to the plasma membrane. Moesin is localized to filopodia and other membranous extensions of various cell types and thus plays a role in cell-cell recognition signaling, cell movement, and cell transport. In its inactive, non-phosphorylated state, Moesin binds itself in a head-tail fashion and is incapable of binding actin or other cytoskeletal proteins. The kinase ROCK2 is central to the opening up of moesin and allowing its interaction with actin and the plasma membrane.

ALT Names :

Moesin;Membrane-organizing extension spike protein

Immunogen :

Recombinant protein corresponding to bovine Moesin.

Package Size :

100 µL

Uses :

Western Blotting;Flow Cytometry;Immunoprecipitation;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt