Stabilin-Interacting Chitinase-like Protein Antibody, clone 1C11 | EMD Millipore MABT22 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Stabilin-Interacting Chitinase-like Protein Antibody, clone 1C11

catalog :

MABT22

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

Jul 1C11

reactivity :

human

application :

western blot, immunocytochemistry

product information

Catalog Number :

MABT22

Subcategory :

Cell Structure

Product Name :

Anti-Stabilin-Interacting Chitinase-like Protein Antibody, clone 1C11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9BWS9

Host Name :

Rat

Antigen :

Stabilin-Interacting Chitinase-like Protein

Clone :

Jul 1C11

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Stabilin-Interacting Chitinase-like Protein Antibody, clone 1C11

Cross Reactivity :

Human

Background :

Stabilin-1-interacting chitinase-like protein (SI-CLP) is a novel protein belonging to the Glyco-18 domain-containing protein family which consists of both true enzymes and secreted chitinase-like proteins that lack enzymatic activity. SI-CLP is secreted by macrophages, and is bound by stabilin-1 which acts to mediate the intracellular sorting of SI-CLP, trafficking it from the trans-golgi network to the system of endosomes and lysosomes. After SI-CLP disassociates from stabilin-1, it is then moved to secretory lysosomes where it is able to be secreted into extracellular space. Currently three isoforms of SI-CLP have been identified; however, the exact function of SI-CLP is yet unknown. Its closest homologues have been implicated as soluble mediators in tumor progression and several disorders involving ECM remodeling and alterations to the vascular system.

ALT Names :

chitinase domain-containing 1;Stabilin-1-interacting chitinase-like protein

Immunogen :

GST-tagged recombinant protein corresponding to human Stabilin-Interacting Chitinase-like Protein.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt