Actin Antibody, clone JLA20 | EMD Millipore MABT219 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Actin Antibody, clone JLA20

catalog :

MABT219

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

JLA20

reactivity :

human, mouse, chicken

application :

western blot, immunocytochemistry

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig s5	Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, et al. Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget. 2016;7:15065-92 pubmed publisher
western blot; human; fig 2 western blot; mouse; fig 1	Vivar O, Masi G, Carpier J, Magalhaes J, Galgano D, Pazour G, et al. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016;113:386-91 pubmed publisher
western blot; human; fig 1	Navarro F, Lieberman J. miR-34 and p53: New Insights into a Complex Functional Relationship. PLoS ONE. 2015;10:e0132767 pubmed publisher
	Baraldo G, Etemad S, Weiss A, Jansen Durr P, Mack H. Modulation of serotonin signaling by the putative oxaloacetate decarboxylase FAHD-1 in Caenorhabditis elegans. PLoS ONE. 2019;14:e0220434 pubmed publisher
	Martín Pardillos A, Valls Chiva Á, Bande Vargas G, Hurtado Blanco P, Piñeiro Cid R, Guijarro P, et al. The role of clonal communication and heterogeneity in breast cancer. BMC Cancer. 2019;19:666 pubmed publisher
	Bärenz F, Kschonsak Y, Meyer A, Jafarpour A, Lorenz H, Hoffmann I. Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry. Mol Biol Cell. 2018;:mbcE18020115 pubmed publisher
	Ferino A, Miglietta G, Picco R, Vogel S, Wengel J, Xodo L. MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells. RNA Biol. 2018;15:1273-1285 pubmed publisher
	Schumacher J, Kong B, Pan Y, Zhan L, Sun R, Aa J, et al. The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis. Toxicol Appl Pharmacol. 2017;330:1-8 pubmed publisher
	Lei W, Myers K, Rui Y, Hladyshau S, Tsygankov D, Zheng J. Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulates synapse development and plasticity. J Cell Biol. 2017;216:2551-2564 pubmed publisher
	Fritz Laylin L, Lord S, Mullins R. WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility. J Cell Biol. 2017;216:1673-1688 pubmed publisher
	da Silva Lima V, Crajoinas R, Carraro Lacroix L, Godinho A, Dias J, Dariolli R, et al. Uroguanylin inhibits H-ATPase activity and surface expression in renal distal tubules by a PKG-dependent pathway. Am J Physiol Cell Physiol. 2014;307:C532-41 pubmed publisher
	Taniuchi K, Furihata M, Iwasaki S, Tanaka K, Shimizu T, Saito M, et al. RUVBL1 directly binds actin filaments and induces formation of cell protrusions to promote pancreatic cancer cell invasion. Int J Oncol. 2014;44:1945-54 pubmed publisher
	Wang Q, Na B, Ou J, Pulliam L, Yen T. Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. PLoS ONE. 2012;7:e36818 pubmed publisher
	Crajoinas R, Oricchio F, Pessoa T, Pacheco B, Lessa L, Malnic G, et al. Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1. Am J Physiol Renal Physiol. 2011;301:F355-63 pubmed publisher
	Crajoinas R, Lessa L, Carraro Lacroix L, Davel A, Pacheco B, Rossoni L, et al. Posttranslational mechanisms associated with reduced NHE3 activity in adult vs. young prehypertensive SHR. Am J Physiol Renal Physiol. 2010;299:F872-81 pubmed publisher
	Girardi A, Fukuda L, Rossoni L, Malnic G, Reboucas N. Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule. Am J Physiol Renal Physiol. 2008;294:F414-22 pubmed
	Fogel A, Akins M, Krupp A, Stagi M, Stein V, Biederer T. SynCAMs organize synapses through heterophilic adhesion. J Neurosci. 2007;27:12516-30 pubmed
	Haithcock E, Dayani Y, Neufeld E, Zahand A, Feinstein N, Mattout A, et al. Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2005;102:16690-5 pubmed

product information

Catalog Number :

MABT219

Subcategory :

Cell Structure

Product Name :

Anti-Actin Antibody, clone JLA20

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P68139

Host Name :

Mouse

Antigen :

Actin

Clone :

JLA20

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-Actin Antibody, clone JLA20

Cross Reactivity :

Human;Chicken

Background :

Actin is an abundantly expressed in eukaryotic cells and it is the core component of the cytoskeleton. It exists in three isoforms: alpha actin, which is found in muscle tissue and forms fibrous actin that facilitates muscle contractility; and beta and gamma actin which are found in non-muscle cells and facilitate cell motility. Actin exists initially as globular actin (G-actin) which is converted to filamentous actin (F-actin) upon assembly. The formation of F-actin is a complex multistep process that is tightly regulated by signaling from the actin-binding proteins (ABPs) and Rho family GTPases. Filamentous actin is crosslinked with other actin polymers to form a complex cytoskeletal network which is required for exo- and phagocytosis, vesicular trafficking, cell migration, and gene regulation, among other cellular processes.

ALT Names :

Actin, alpha skeletal muscle;Alpha-actin-1

Immunogen :

Chicken cytoskeletal proteins

Package Size :

100 µL

Uses :

Western Blotting;Immunofluorescence

Storage :

Stable for 1 year at 2-8°C from date of receipt