Integrin alpha-V Antibody, clone 272-17E6 (Azide free) | EMD Millipore MABT207 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin alpha-V Antibody, clone 272-17E6 (Azide free)

catalog :

MABT207

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

272-17E6

The same clone is also sold as:

Abcam: ab16821
Invitrogen: MA1-91669

reactivity :

human

application :

immunoprecipitation, flow cytometry, blocking or activating experiments

citations: 5

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...	Bon H, Hales P, Lumb S, Holdsworth G, Johnson T, Qureshi O, et al. Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins. Nephron. 2019;:1-23 pubmed publisher
flow cytometry; human; loading ...; fig 1	Nestić D, Uil T, Ma J, Roy S, Vellinga J, Baker A, et al. αvβ3 Integrin Is Required for Efficient Infection of Epithelial Cells with Human Adenovirus Type 26. J Virol. 2019;93: pubmed publisher
flow cytometry; human	Majhen D, Stojanović N, Vukić D, Pichon C, Leduc C, Osmak M, et al. Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation. PLoS ONE. 2014;9:e86698 pubmed publisher
	Stockis J, Li nart S, Colau D, Collignon A, Nishimura S, Sheppard D, et al. Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8. Proc Natl Acad Sci U S A. 2017;114:E10161-E10168 pubmed publisher
	Brilha S, Wysoczanski R, Whittington A, Friedland J, Porter J. Monocyte Adhesion, Migration, and Extracellular Matrix Breakdown Are Regulated by Integrin ?V?3 in Mycobacterium tuberculosis Infection. J Immunol. 2017;199:982-991 pubmed publisher

product information

Catalog Number :

MABT207

Subcategory :

Cell Structure

Product Name :

Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free)

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06756

Host Name :

Mouse

Antigen :

Integrin alpha-V

Clone :

272-17E6

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free)

Cross Reactivity :

Human

Background :

Integrin alpha-V (or CD51; vitronectin receptor subunit alpha) protein is a transmembrane receptor that mediates adhesion of cells to each other and to the extracellular matrix. Integrin receptors are activated by a variety of intracellular signals that modify its cytoplasmic domain and induce configural changes in integrin molecules thereby enabling ligand binding to the extracellular surface. An important part of this process is the binding of the actin protein, talin, to the integrin cytoplasmic domain.

ALT Names :

Integrin alpha-V;Vitronectin receptor subunit alpha;CD51;Integrin alpha-V heavy chain;Integrin alpha-V light chain;Intergrin av

Immunogen :

Human Placental ɑvβ3

Package Size :

100 μg

Uses :

Flow Cytometry;Immunoprecipitation;Activity Assay

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.