Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51 | EMD Millipore MABT201 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51

catalog :

MABT201

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SNAKA51

reactivity :

human

application :

western blot, immunocytochemistry

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; loading ...; fig 1e	Li B, He J, Lv H, Liu Y, Lv X, Zhang C, et al. c-Abl regulates YAPY357 phosphorylation to activate endothelial atherogenic responses to disturbed flow. J Clin Invest. 2019;129:1167-1179 pubmed publisher
	Roman W, Martins J, Gomes E. Local Arrangement of Fibronectin by Myofibroblasts Governs Peripheral Nuclear Positioning in Muscle Cells. Dev Cell. 2018;46:102-111.e6 pubmed publisher
	Erdoğan B, Ao M, White L, Means A, Brewer B, Yang L, et al. Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. J Cell Biol. 2017;216:3799-3816 pubmed publisher
	Georgiadou M, Lilja J, Jacquemet G, GuzmÃ¡n C, Rafaeva M, Alibert C, et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol. 2017;216:1107-1121 pubmed publisher

product information

Catalog Number :

MABT201

Subcategory :

Cell Structure

Product Name :

Anti-Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06756

Host Name :

Mouse

Antigen :

Integrin alpha5 (Preservative Free)

Clone :

SNAKA51

Conjugate :

Protein G Purified

Isotype :

IgG 2α

Product Description :

Anti-Integrin alpha5 (Preservative Free) Antibody, clone SNAKA51

Cross Reactivity :

Human

Background :

Integrins are a family of dimeric, transmembrane proteins that mediate cell-cell and extracellular matrix adhesion. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. The integrin family is composed of at least 15 alpha and 8 beta subunits that may form over twenty different alpha-beta non-covalently bound dimeric combinations on the cell surface. The alpha subunits all have some homology to each other, as do the beta subunits. Both of the subunits contribute to the binding of the ligand. Integrin alpha subunits contain seven weak sequence repeats in the N-terminal region, which may be important in ligand binding, and have been predicted to fold cooperatively into a single beta-propeller domain with seven beta-sheets. The α5/β1 integrin, also termed VLA5 or CD49e, is identical to the fibronectin receptor and mediates the adhesion of cells to fibronectin.

ALT Names :

Integrin alpha-V; Vitronectin receptor subunit alpha; CD51

Immunogen :

Whole cells corresponding to human Integrin alpha5.

Package Size :

100 μg

Uses :

Western Blotting;Activity Assay;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt.