Rab5A Antibody, clone 7D8.1 | EMD Millipore MABT182 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rab5A Antibody, clone 7D8.1

catalog :

MABT182

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7D8.1

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABT182

Subcategory :

Cell Structure

Product Name :

Anti-Rab5A Antibody, clone 7D8.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P20339

Host Name :

Mouse

Antigen :

RAB5A

Clone :

7D8.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-Rab5A Antibody, clone 7D8.1

Cross Reactivity :

Human

Background :

Rab5A is a membrane associated Ras related GTPase that is required for endosome fusion with the plasma membrane. Rab5A also contributes to filopodia extension and other cellular cytoplasmic extensions. Rab5A plays important roles in cellular differentiation, neurogenesis, exocytosis and protein transport. Rab proteins are a large family of GTP-binding proteins that regulate cellular membrane traffic and organelle identity. When membrane bound, each Rab has a very specific cellular location and recognizes distinct subsets of intracellular membranes, which allows Rab proteins to act as as key cellular regulators, determining the recruitment of downstream effectors to the correct membrane at the correct time. Recent research indicates that the localization of Rab proteins happens by sensing the stored curvature elastic energy in the membrane and the specific RabGEFs (Rab-activating guanosine diphosphate/guanosine triphosphate exchange factors) that associate with a particular Rab. Rab5A associates with Rabex-5 and this association provides the determinants for Rab5A specific membrane targets.

ALT Names :

Ras-related protein Rab-5A, Rab5

Immunogen :

KLH-conjugated linear peptide corresponding to human Rab5A.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt