Gamma-1-Tubulin, clone 6H3.1 | EMD Millipore MABT163 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Gamma-1-Tubulin, clone 6H3.1

catalog :

MABT163

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H3.1

reactivity :

human

application :

western blot, immunocytochemistry

product information

Catalog Number :

MABT163

Subcategory :

Cell Structure

Product Name :

Anti-Gamma-1-Tubulin, clone 6H3.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P23258

Host Name :

Mouse

Antigen :

TUBG1

Clone :

6H3.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-Gamma-1-Tubulin, clone 6H3.1

Cross Reactivity :

Human

Background :

Gamma-1-Tubulin, also known as Gamma-tubulin complex component 1, GCP-1 or Tubulin gamma-1 chain, and encoded by the gene TUBG1/TUBG, is a form of tubulin protein and a component of microtubules. Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome and plays a major role in the organization of the microtubule cytoskeleton. Gamma-1-Tubulin is part of the pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, and it is also involved in centrosome duplication and spindle formation. Interestingly, gamma tubulin is often up regulated but improperly compartmentalized in many cancer cells including non-small cell lung cancer. Mutations in Gamma-1-Tubulin gene are associated with developmental cortical defects including microcephaly and malformations of cortical development (MCD). Gamma-1-Tubulin is localized to the cytoplasm and cytoskeleton components and expressed in a variety of cell types and tissues.

ALT Names :

Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1

Immunogen :

GST-tagged recombinant protein corresponding to human Gamma-1-Tubulin.

Package Size :

100 μg

Uses :

Western Blotting, Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt