VE-Cadherin Antibody (CD144), clone BV9 | EMD Millipore MABT129 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

VE-Cadherin Antibody (CD144), clone BV9

catalog :

MABT129

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BV9

The same clone is also sold as:

Invitrogen: MA1-198
BioLegend: 348515, 348512, 348516, 348502, 348501, 348506, 348519, 348505, 348513, 348521, 348514, 348508, 348510, 348507, 348517, 348520, 348509
OriGene: AM26286FC-N, AM26286PU-N
Novus Biologicals: NB600-1409
LifeSpan Biosciences: LS-C139965, LS-C139964
Santa Cruz Biotechnology: sc-52751

reactivity :

human

application :

immunohistochemistry, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:200	Pienaar I, Lee C, Elson J, McGuinness L, Gentleman S, Kalaria R, et al. Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease. Neurobiol Dis. 2015;74:392-405 pubmed publisher
	Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, et al. Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations. EMBO Mol Med. 2018;10: pubmed publisher

product information

Catalog Number :

MABT129

Subcategory :

Cell Structure

Product Name :

Anti-VE-Cadherin Antibody (CD144), clone BV9

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P33151

Host Name :

Mouse

Antigen :

VE-Cadherin (CD144)

Clone :

BV9

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-VE-Cadherin Antibody (CD144), clone BV9

Cross Reactivity :

Human

Background :

Also known as CD144, human Vascular Endothelial (VE)-cadherin is a calcium-dependent adhesion molecule strictly located at cell to cell junctions. VE-cadherin is present in all types of endothelium (veins, arteries, capillary and large vessels). Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherins are reported to play an important role in angiogeneis and in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha catenin forming a link to the cytoskeleton.

ALT Names :

Cadherin-5;7B4 antigen;Vascular endothelial cadherin;VE-cadherin;CD144

Immunogen :

Recombinant protein corresponding to the extracellular domain of human VE-Cadherin.

Specificity :

This antibody recognizes the extracellular domain of VE-Cadherin.

Package Size :

100 µL

Uses :

Immunocytochemistry;Enzyme Assay

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.