Aggrecan Antibody, clone 7D1 | EMD Millipore MABT109 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Aggrecan Antibody, clone 7D1

catalog :

MABT109

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7-D-1

reactivity :

rat, bovine

application :

western blot

product information

Catalog Number :

MABT109

Subcategory :

Cell Structure

Product Name :

Anti-Aggrecan Antibody, clone 7D1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P07897

Host Name :

Mouse

Antigen :

Aggrecan

Clone :

7-D-1

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-Aggrecan Antibody, clone 7D1

Cross Reactivity :

Bovine

Background :

Aggrecan (CSPG1, CSPCP, or CSPGCP) is a chondroitin-sulfate proteoglycan belonging to the family of letican proteins. Aggrecan is a large globar structure containing multiple domains including carbohydrate-recognition domains; complement binding protein domains; immunoglobulin domains; proteoglycan tandem repeats; and in some cases, EGF-like domains. It can be degraded by aggrecanase. The N-terminus of aggrecan binds ECM hyaluronan in the presence of the linking protein, and forms complex aggregates, whereas the C-terminus binds a number of other ECM proteins including tenascins, glycolipids, and fibulins. Aggrecan is a major component of cartilage tissue and it enables this tissue to withstand compression by maintaining the viso-elastic properties of cartilage. Aggrecan may also facilitate neural maturation and plasticity by contributing to the formation of perineuronal nets in the developing CNS.

ALT Names :

Aggrecan core protein;Cartilage-specific proteoglycan core protein;CSPCP

Immunogen :

Other corresponding to A1D1-OH of rat chondrosarcoma aggrecan.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt