GRB-2 Antibody, clone 7G10.1 | EMD Millipore MABS89 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GRB-2 Antibody, clone 7G10.1

catalog :

MABS89

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7G10.1

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

MABS89

Subcategory :

Cell Signaling

Product Name :

Anti-GRB-2 Antibody, clone 7G10.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P62993

Host Name :

Mouse

Antigen :

GRB-2

Clone :

7G10.1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-GRB-2 Antibody, clone 7G10.1

Cross Reactivity :

Human;Mouse;Rat

Background :

GRB-2 (growth factor receptor-bound protein 2) is structurally and functionally similar to the C. elegans protein sem-5. GRB-2 contains one src homology 2 (SH2) domain and two SH3 domains that interact with EGFRs and PDGFRs and seems to be play an important part in the growth factor control of ras signaling. Ras signaling is involved in cell proliferation and differentiation and GRB-2 may be involved in the development of cancer cells. GRB-2 has also been found to have an impact on apoptosis. Recently, GRB-2 signaling has been found to be critical for lymphocyte differentiation and secondary humoral immune responses.

ALT Names :

Growth factor receptor-bound protein 2;Adapter protein GRB2;Protein Ash;SH2/SH3 adapter GRB2

Immunogen :

Recombinant protein corresponding to human GRB-2.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt