GPR177 Antibody, clone YJ5 | EMD Millipore MABS87 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GPR177 Antibody, clone YJ5

catalog :

MABS87

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

YJ5

The same clone is also sold as:

BioLegend: 655902

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Stewart J, James J, McCluggage G, McQuaid S, Arthur K, Boyle D, et al. Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression. Mod Pathol. 2015;28:428-36 pubmed publisher
	Menck K, Klemm F, Gross J, Pukrop T, Wenzel D, Binder C. Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget. 2013;4:2057-66 pubmed
	Najdi R, Proffitt K, Sprowl S, Kaur S, Yu J, Covey T, et al. A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities. Differentiation. 2012;84:203-13 pubmed publisher

product information

Catalog Number :

MABS87

Subcategory :

Cell Signaling

Product Name :

Anti-GPR177 Antibody, clone YJ5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q5T9L3

Host Name :

Mouse

Antigen :

GPR177

Clone :

YJ5

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-GPR177 Antibody, clone YJ5

Cross Reactivity :

Human

Background :

Gpr177 (WLS, EVI), the mouse ortholog of Drosophila WIs, is expressed during mouse embryogenesis. It is essential for the patterning of the anterior-posterior axis during mammalian development and is activated by â-catenin and LEF/TCF-dependent transcription. Upon GPR177 activation, Wnt binds with and modifies the cellular distribution of GPR177, leading to a feedback regulatory mechanism involving Wnt expression and signaling.

ALT Names :

Protein wntless homolog; Integral membrane protein GPR177;Protein evenness interrupted homolog;Putative NF-kappa-B-activating protein 373;WLS;EVI

Immunogen :

Histidine-tagged recombinant protein corresponding to human GPR177.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt