NDR1/2 protein kinase Antibody, clone BH6-31G14 | EMD Millipore MABS56 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

NDR1/2 protein kinase Antibody, clone BH6-31G14

catalog :

MABS56

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BH6-31G14

reactivity :

human

application :

western blot, ELISA

citations: 1

Reference
Chakraborty A, Prasanth K, Prasanth S. Dynamic phosphorylation of HP1? regulates mitotic progression in human cells. Nat Commun. 2014;5:3445 pubmed publisher

product information

Catalog Number :

MABS56

Subcategory :

Cell Signaling

Product Name :

Anti-NDR1/2 protein kinase Antibody, clone BH6-31G14

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q15208

Host Name :

Mouse

Antigen :

NDR1/2 protein kinase

Clone :

BH6-31G14

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-NDR1/2 protein kinase Antibody, clone BH6-31G14

Cross Reactivity :

Human

Background :

Nuclear DFB-2-related (NDR) kinases are a highly conserved, subclass of the AGC protein kinase group that are known to be regulated by Mps One Binding (MOB) binding partner through binding and subsequent activation. They can also be activated by phosphorylation to the hydrophobic motif at the C-terminal and the kinase domain activation loop. NDR kinases play an integral role as regulators in several cellular processes such as; cytokinesis, mitotic exit, centrosome duplication, cell growth, morphogenesis, and development. NDR1 and NDR2 are two serine-threonine kinases belonging to the NDR kinase family that share significant homology with each other. NDR1 autophosphorylation is induced by Ca2+ in addition to phosphorylation by an unknown upstream kinase. Both NDR1 and NDR2 are nearly ubiquitous in expression, with the exception of NDR1 not being observed in the brain. In contrast, NDR2 has highest expression in the thymus. Studies have suggested the NDR1 may be involved in tumor progression and NDR2 in either tumor initiation or progression.

ALT Names :

serine/threonine kinase 38;nuclear Dbf2-related 1;NDR1 protein kinase;Nuclear Dbf2-related kinase 1;Ndr Ser/Thr kinase-like protein;serine threonine protein kinase

Immunogen :

Mal-tagged (Maltose Binding Protein) recombinant protein corresponding to human NDR1/2 kinase protein.

Specificity :

This antibody recognizes NDR1/2 kinase protein.

Package Size :

100 μg

Uses :

Western Blotting;ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt