PPM1A, clone 7F12 Antibody | EMD Millipore MABS415 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PPM1A, clone 7F12 Antibody

catalog :

MABS415

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7F12

The same clone is also sold as:

ProMab: 30376
Novus Biologicals: NBP2-37480
Invitrogen: MA5-17154

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog Number :

MABS415

Subcategory :

Cell Signaling

Product Name :

Anti-PPM1A, clone 7F12 Antibody

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P35813

Host Name :

Mouse

Antigen :

PPM1A

Clone :

7F12

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1

Product Description :

Anti-PPM1A, clone 7F12 Antibody

Cross Reactivity :

Human

Background :

Protein phosphatase 1A, also known as Protein phosphatase 2C isoform alpha (PP2C-alpha) or Protein phosphatase IA, and encoded by the gene name PPM1A, is a member of the PP2C family. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis.

ALT Names :

Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA, PPM1A

Immunogen :

Purified recombinant fragment of human PPM1A expressed in E. Coli

Package Size :

100 µL

Uses :

Western Blotting, Flow Cytometry, ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt