FAT10 Antibody, clone 4F1 | EMD Millipore MABS351 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

FAT10 Antibody, clone 4F1

catalog :

MABS351

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4F1

The same clone is also sold as:

Enzo Life Sciences: BML-PW0765-0025, BML-PW0765-0100

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Catalog Number :

MABS351

Subcategory :

Cell Signaling

Product Name :

Anti-FAT10 Antibody, clone 4F1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O15205

Host Name :

Mouse

Antigen :

FAT10

Clone :

4F1

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-FAT10 Antibody, clone 4F1

Cross Reactivity :

Human;Mouse;Rat

Background :

FAT10 protein is a recombinant protein produced in E. coli corresponding to the human sequence encompassing an N-terminal His6-tag within a leader sequence. FAT10, a ubiquitin-like protein, is encoded in the major histocompatibility complex class I locus and is synergistically inducible with interferon-gamma and tumor necrosis factor alpha. FAT10 expression causes apoptosis and it appears that FAT10 may modulate tumorigenesis through its interaction with the MAD2 spindle-assembly checkpoint protein. It has been demonstrated that FAT10 and its conjugates are rapidly degraded by the proteasome. Furthermore, a new interaction partner of FAT10, NEDD8 ultimate buster-1L (NUB1L), may function as a linker that targets FAT10 for degradation by the proteasome.

ALT Names :

Ubiquitin D;Diubiquitin;Ubiquitin-like protein FAT10

Immunogen :

GST-tagged recombinant protein corresponding to human FAT10.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt