Abl interactor 1 Antibody, clone W8-3 | EMD Millipore MABS273 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Abl interactor 1 Antibody, clone W8-3

catalog :

MABS273

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

W8-3

reactivity :

human, pigs

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; pigs ; loading ...; fig 3 western blot; pigs ; loading ...; fig 1d,3 immunoprecipitation; human; loading ...; fig 3 western blot; human; loading ...; fig 1c	Betzer C, Movius A, Shi M, Gai W, Zhang J, Jensen P. Identification of synaptosomal proteins binding to monomeric and oligomeric Î±-synuclein. PLoS ONE. 2015;10:e0116473 pubmed publisher

product information

Catalog Number :

MABS273

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Abl interactor 1 Antibody, clone W8-3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8IZP0

Host Name :

Mouse

Antigen :

Abl interactor 1

Clone :

W8-3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Abl interactor 1 Antibody, clone W8-3

Cross Reactivity :

Human

Background :

Abl interactor 1 (Abelson interactor 1, Abi-1, e3B1) is a member of the family of Abl-interactors and is highly expressed in the brain. Abl interactor 1 is involved in the signaling of ABL1 and ABL2 nonreceptor tyrosine kinases, and the EGF-receptor. The Abl interactor 1 protein contains SH3 domains, and may function as an adaptor protein: It forms a trimeric complex with EPS8 and SOS1 in the transduction of signals from Ras to Rac. Previous studies have suggested that Abl interactor 1 via the Ras and Rac pathways may regulate cell proliferation, cell adhesion, and actin remodeling. Abl interactor 1 is also investigated for its role in tumor suppression.

ALT Names :

Abl interactor 1;Abelson interactor 1;Abi-1;AblBP4;Eps8 SH3 domain-binding protein;Eps8-binding protein;Eps8-binding protein;Nap1-binding protein;Nap1-binding protein;Nap1BP;Spectrin SH3 domain-binding protein 1;e3B1

Immunogen :

Linear peptide corresponding to human Abl interactor 1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt