PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3 | EMD Millipore MABS270 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3

catalog :

MABS270

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5A5-1F3

reactivity :

human, Xenopus laevis

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; Xenopus laevis; 1 ug/ml	Kang Q, Srividhya J, Ipe J, Pomerening J. Evidence toward a dual phosphatase mechanism that restricts Aurora A (Thr-295) phosphorylation during the early embryonic cell cycle. J Biol Chem. 2014;289:17480-96 pubmed publisher
	He H, Brenier Pinchart M, Braun L, Kraut A, Touquet B, Coute Y, et al. Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation. elife. 2018;7: pubmed publisher

product information

Catalog Number :

MABS270

Subcategory :

Neuroscience

Product Name :

Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q16537

Host Name :

Mouse

Antigen :

PP2A reg. subunit B56 epsilon (PPP2R5E)

Clone :

5A5-1F3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3

Cross Reactivity :

Human;Mouse

Background :

Protein phosphatase 2A (PP2A) is a family of ubiquitous heterotrimeric proteins that catalyze the removal of phosphate groups from serine and threonine residues. The PP2A enzymes contain core structural (A) and catalytic (C) subunits and variable regulatory B subunits. The B subunits regulate their catalytic activity, as well as dictate substrate specificity and subcellular localization. Recent studies have suggested that B56 epsilon subunits regulate p53-mediated apoptotic pathways, and can induce or suppress apoptosis depending on the cellular context. PP2A enzymes are also regulated by posttranslational modifications and endogenous inhibitors.

ALT Names :

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform;PP2A B subunit isoform B'-epsilon; PP2A B subunit isoform B56-epsilon;PP2A B subunit isoform PR61-epsilon;PP2A B subunit isoform R5-epsilon

Immunogen :

His-tagged recombinant protein corresponding to human PP2A reg. subunit B56 epsilon (PPP2R5E).

Specificity :

This antibody is specific for the B56 regulatory subunit of Protein phosphatase 2A (PP2A).

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt